Hyperuricosuria

Our DNA test for Hyperuricosuria is ideal for breeders and owners who want the reassurance of genetic health testing.

The guideline turnaround time for single tests is approximately 10-12 working days after the swab arrives at the lab. 

If you need more than two tests it is often more cost-effective to order the relevant breed package.

Description

Hyperuricosuria (HUU) is a disorder which causes high levels of uric acid in the urine which can cause crystals or stones in the urinary tract. It can also cause loss of appetite, weakness, and vomiting.

An autosomal recessive condition caused by a mutation in the SLC2A9 gene.

Breeds

This test is also included in the following breed packages:

• Australian Labradoodle
• Australian Shepherd
• Bulldog
• Cockerdor
• Dalmatian
• Finnish Lapphund
• French Bulldog
• German Shepherd
• Giant Schnauzer
• Hungarian Wire Haired Vizsla
• Jack Russell Terrier
• Labradoodle
• Labrador Essential
• Lagotto Romagnolo
• Large Munsterlander
• Parson Russell Terrier
• Rottweiler
• Rough Collie
• Russian Black Terrier
• Schnoodle
• Smooth Collie
• Spanish Water Dog
• Whippet

Scientific references:

Bannasch D, Safra N, Young A, Karmi N, Schaible RS, Ling GV. Mutations in the SLC2A9 gene cause hyperuricosuria and hyperuricemia in the dog. PLoS Genet. 2008 Nov;4(11):e1000246

Karmi N, Brown EA, Hughes SS, McLaughlin B, Mellersh CS, Biourge V, Bannasch DL. Estimated frequency of the canine hyperuricosuria mutation in different dog breeds. J Vet Intern Med. 2010 Nov-Dec;24(6):1337-42