Primary Lens Luxation

Our test for Primary Lens Luxation is ideal for breeders and owners who want the reassurance of genetic health testing.

The guideline turnaround time for single tests is approximately 10-12 working days after the swab arrives at the lab. 

If you need more than two tests it is often more cost-effective to order the relevant breed package.

Description

Primary Lens Luxation (PLL) is an eye disorder which causes dislocation of the lens. Onset is variable but typically beyond two years of age, causing excessive blinking, squinting, tearing. If not treated it can lead to glaucoma and blindness.

An autosomal recessive condition caused by a mutation in the ADAMTS17 gene.

Scientific references:

Gould D, Pettitt L, McLaughlin B, Holmes N, Forman O, Thomas A, Ahonen S, Lohi H, O'Leary C, Sargan D, Mellersh C. ADAMTS17 mutation associated with primary lens luxation is widespread among breeds. Vet Ophthalmol. 2011 Nov;14(6):378-84