Exercise Induced Collapse

Exercise Induced Collapse (EIC) is a neuromuscular disorder. After strenuous activity affected dogs will display hindlimb weakness and incoordination with usually a return to normal after around 30 minutes.

An autosomal recessive condition caused by a mutation in the DNM1 gene.

Furrow E, Minor KM, Taylor SM, Mickelson JR, Patterson EE. Relationship between dynamin 1 mutation status and characteristics of recurrent episodes of exercise-induced collapse in Labrador Retrievers. J Am Vet Med Assoc. 2013 Mar 15;242(6):786-91

Minor KM, Patterson EE, Keating MK, Gross SD, Ekenstedt KJ, Taylor SM, Mickelson JR. Presence and impact of the exercise-induced collapse associated DNM1 mutation in Labrador retrievers and other breeds. Vet J. 2011 Aug;189(2):214-9