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Cobalamin Malabsorption

Original price £48.00 - Original price £48.00
Original price
£48.00 - £48.00
Current price £48.00

Our DNA test for Cobalamin Malabsorption is ideal for breeders and owners who want the reassurance of genetic health testing.

If you need more than two tests it is often more cost-effective to order the relevant breed package.


Cobalamin Malabsorption or Imerslund-Grasbeck Syndrome (IGS) is an inability of the intestine to properly absorb B12 which is needed for cell growth and in the nervous system. Early signs include a loss of appetite and energy, and abnormal growth.

Imerslund-Grasbeck Syndrome is an autosomal recessive condition caused by a mutation in the CUBN gene.


This test is also included in the following breed packages:

  • Beagle
  • Border Collie


Scientific references:

Kather S, Grützner N, Kook PH, Dengler F, Heilmann RM. Review of cobalamin status and disorders of cobalamin metabolism in dogs. J Vet Intern Med. 2020 Jan;34(1):13-28

He Q, Fyfe JC, Schäffer AA, Kilkenney A, Werner P, Kirkness EF, Henthorn PS. Canine Imerslund-Gräsbeck syndrome maps to a region orthologous to HSA14q. Mamm Genome. 2003 Nov;14(11):758-64