R-Locus (roan)

£30.00

The R-Locus is a region of your dog's DNA which controls whether your dog has roaning on their coat. Roaning consists of pigmented and unpigmented (white) hairs interspersed evenly without the formation of distinct spots. Roan colouration often develops over time meaning the pups can appear non-roan and will only gain their true roan appearance once fully grown.

Your dog can only be roan if it also carries some form of white spotting, the roan pattern would not be visible on a solid colour dog.

Ticking is similar to roaning and sometimes co-occurs, but is characterized by small pigmented spots of varying number and size appearing on otherwise unpigmented (white) areas.

Please note although the ticking pattern can be similar to roan this is controlled by a separate gene which is not yet testable and will not be indicated on this test.

The roan colourations are caused by mutations on the USH2A gene. Roan is dominant, meaning only one copy is needed for the roaning pattern to occur.

Results:

Your results will be reported as one combination of the R-locus alleles with the following interpretations.

R/R - roan
R/N - roan, carrying non-roan
N/N - non-roan

 

Scientific references:

Kawakami T, Jensen MK, Slavney A, Deane PE, Milano A, Raghavan V, Ford B, Chu ET, Sams AJ, Boyko AR. R-locus for roaned coat is associated with a tandem duplication in an intronic region of USH2A in dogs and also contributes to Dalmatian spotting. PLoS One. 2021 Mar 23;16(3):e0248233

 

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