Foresight Health® Shaking Puppy Syndrome


Our Foresight Health® single test for Shaking Puppy Syndrome is ideal for breeders and owners who want the reassurance of genetic health testing.

Our DNA test results are accepted by the Kennel Club.

The guideline turnaround time for single tests is approximately 10-12 working days after the swab arrives at the lab. 

If you need more than two tests it is often more cost-effective to order the relevant Foresight Health® breed package.


Shaking Puppy Syndrome affects myelination of the spinal cord causing a generalised tremor from around two weeks of age. The tremor severity can be variable but diminishes by around three or four months of age.

An X-linked recessive condition caused by a mutation in the PLP1 gene.


This test is also included in the following Foresight Health® breed packages:


Scientific references:

Nadon NL, Duncan ID, Hudson LD. A point mutation in the proteolipid protein gene of the 'shaking pup' interrupts oligodendrocyte development. Development. 1990 Oct;110(2):529-37

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