Foresight Health® Pyruvate Kinase Deficiency
Our Foresight Health® single test for Pyruvate Kinase Deficiency is ideal for breeders and owners who want the reassurance of genetic health testing.
Our DNA test results are accepted by the Kennel Club.
Pyruvate Kinase Deficiency (PKD) causes easily damaged red blood cells and can cause anaemia and exercise intolerance. Affected dogs often die from severe anaemia or liver failure by five to nine years of age.
An autosomal recessive condition caused by a mutation in the PKLR gene.
This test is also included in the following Foresight Health® breed packages:
The guideline turnaround time for single tests is approximately 10-12 working days after the swab arrives at the lab.
If you need more than two tests it is often more cost-effective to order the relevant Foresight Health® breed package.
Gultekin GI, Raj K, Foureman P, Lehman S, Manhart K, Abdulmalik O, Giger U. Erythrocytic pyruvate kinase mutations causing hemolytic anemia, osteosclerosis, and seconday hemochromatosis in dogs. J Vet Intern Med. 2012 Jul-Aug;26(4):935-44