Foresight Health® Osteogenesis Imperfecta


Our Foresight Health® single test for Osteogenesis Imperfecta is ideal for breeders and owners who want the reassurance of genetic health testing.

The guideline turnaround time for single tests is approximately 10-12 working days after the swab arrives at the lab. 

If you need more than two tests it is often more cost-effective to order the relevant Foresight Health® breed package.


Osteogenesis Imperfecta (OI) is a collagen disorder starting at a few weeks of age. It causes lameness and fractures due to thinner than normal bones, as well as loose joints and brittle teeth. Affected dogs are usually euthanised at a young age.

An autosomal recessive condition caused by a mutation in the SERPINH1 or an autosomal dominant condition caused by a mutation in the COL1A1 gene.


This test is also included in the following Foresight Health® breed packages:


Scientific references:

Lindert U, Weis MA, Rai J, Seeliger F, Hausser I, Leeb T, Eyre D, Rohrbach M, Giunta C. Molecular Consequences of the SERPINH1/HSP47 Mutation in the Dachshund Natural Model of Osteogenesis Imperfecta. J Biol Chem. 2015 Jul 17;290(29):17679-17689

Campbell BG, Wootton JA, MacLeod JN, Minor RR. Sequence of normal canine COL1A1 cDNA and identification of a heterozygous alpha1(I) collagen Gly208Ala mutation in a severe case of canine osteogenesis imperfecta. Arch Biochem Biophys. 2000 Dec 1;384(1):37-46

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