Foresight Health® Neuroaxonal Dystrophy

£42.00

Our Foresight Health® single test for Neuroaxonal Dystrophy is ideal for breeders and owners who want the reassurance of genetic health testing.

Our DNA test results are accepted by the Kennel Club.

Description

Neuroaxonal Dystrophy (NAD) is a progressive neurological disease which causes abnormal gait and limb weakness. In the Papillon it may cause paralysis, blindness, and deafness, whilst in the Spanish Water Dog incontinence and nervous behaviour.

An autosomal recessive condition caused by a mutation in the PLA2G6 (Papillon) or TECPR2 (Spanish Water Dog) gene.

Breeds

This test is also included in the following Foresight Health® breed packages:

 

The guideline turnaround time for single tests is approximately 10-12 working days after the swab arrives at the lab. 

If you need more than two tests it is often more cost-effective to order the relevant Foresight Health® breed package.

 

Scientific references:

Raj K, Giger U. Initial survey of PLA2G6 missense variant causing neuroaxonal dystrophy in Papillon dogs in North America and Europe. Canine Med Genet. 2020 Nov 30;7(1):17

Hahn K, Rohdin C, Jagannathan V, Wohlsein P, Baumgärtner W, Seehusen F, Spitzbarth I, Grandon R, Drögemüller C, Jäderlund KH. TECPR2 Associated Neuroaxonal Dystrophy in Spanish Water Dogs. PLoS One. 2015 Nov 10;10(11):e0141824

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