Foresight Health® Ichthyosis

£42.00

Our Foresight Health® single test for Ichthyosis is ideal for breeders and owners who want the reassurance of genetic health testing.

Our DNA test results are accepted by the Kennel Club.

The guideline turnaround time for single tests is approximately 10-12 working days after the swab arrives at the lab. 

If you need more than two tests it is often more cost-effective to order the relevant Foresight Health® breed package.

Description

Ichthyosis (ICT) is a condition resulting in flaky skin and dull hair, which can vary greatly between affected dogs. Dogs are generally otherwise healthy but do have a risk of skin infection.

An autosomal recessive condition caused by a mutation in the PNPLA1 (Type A) or NIPAL4 (American Bulldog Type) gene.

Breeds

This test is also included in the following Foresight Health® breed packages:

 

Scientific references:

Grall A, Guaguère E, Planchais S, Grond S, Bourrat E, Hausser I, Hitte C, Le Gallo M, Derbois C, Kim GJ, Lagoutte L, Degorce-Rubiales F, Radner FP, Thomas A, Küry S, Bensignor E, Fontaine J, Pin D, Zimmermann R, Zechner R, Lathrop M, Galibert F, André C, Fischer J. PNPLA1 mutations cause autosomal recessive congenital ichthyosis in golden retriever dogs and humans. Nat Genet. 2012 Jan 15;44(2):140-7

Casal ML, Wang P, Mauldin EA, Lin G, Henthorn PS. A Defect in NIPAL4 Is Associated with Autosomal Recessive Congenital Ichthyosis in American Bulldogs. PLoS One. 2017 Jan 25;12(1):e0170708

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