Foresight Health® Familial Nephropathy
Our Foresight Health® single test for Familial Nephropathy is ideal for breeders and owners who want the reassurance of genetic health testing.
Our DNA test results are accepted by the Kennel Club.
Familial Nephropathy (FN) is a kidney disease usually showing from six months to two years with abnormal levels of protein in the urine. This causes excessive drinking and urinating, weight loss, and fatigue, which eventually leads to kidney failure and death.
An autosomal recessive condition caused by a mutation in the COL4A4 gene.
This test is also included in the following Foresight Health® breed packages:
- Cockapoo (Cocker Type)
- Cocker Spaniel (Cocker Type)
- Cockerdor (Cocker Type)
- English Springer Spaniel (Springer Type)
- Sprocker (Cocker Type, Springer Type)
The guideline turnaround time for single tests is approximately 10-12 working days after the swab arrives at the lab.
If you need more than two tests it is often more cost-effective to order the relevant Foresight Health® breed package.
Andrade LR, Caceres AM, Trecenti AS, Borges AS, Oliveira-Filho JP. Allele frequency of nonsense mutation responsible for hereditary nephropathy in English cocker spaniel dogs. Vet Anim Sci. 2020 Apr 19;9:100114
Nowend KL, Starr-Moss AN, Lees GE, Berridge BR, Clubb FJ, Kashtan CE, Nabity MB, Murphy KE. Characterization of the genetic basis for autosomal recessive hereditary nephropathy in the English Springer Spaniel. J Vet Intern Med. 2012 Mar-Apr;26(2):294-301