Foresight Health® Ectodermal Dysplasia

Our Foresight Health® single test for Ectodermal Dysplasia is ideal for breeders and owners who want the reassurance of genetic health testing.

The guideline turnaround time for single tests is approximately 10-12 working days after the swab arrives at the lab.

If you need more than two tests it is often more cost-effective to order the relevant Foresight Health^® breed package.

Description

Ectodermal Dysplasia (ED) occurs from birth with affected dogs unable to produce an important skin protein. Skin is fragile and easily sloughs off the nose, footpads, and ears and affected dogs usually die within a few days of birth.

An autosomal recessive condition caused by a mutation in the PKP1 gene.

Breeds

This test is also included in the following Foresight Health^® breed packages:

• Chesapeake Bay Retriever
• Golden Retriever

Scientific references:

Olivry T, Linder KE, Wang P, Bizikova P, Bernstein JA, Dunston SM, Paps JS, Casal ML. Deficient plakophilin-1 expression due to a mutation in PKP1 causes ectodermal dysplasia-skin fragility syndrome in Chesapeake Bay retriever dogs. PLoS One. 2012;7(2):e32072