Foresight Health® Dental Hypomineralisation
Our Foresight Health® single test for Dental Hypomineralisation is ideal for breeders and owners who want the reassurance of genetic health testing.
Our DNA test results are accepted by the Kennel Club.
The guideline turnaround time for single tests is approximately 10-12 working days after the swab arrives at the lab.
If you need more than two tests it is often more cost-effective to order the relevant Foresight Health® breed package.
Dental Hypomineralisation (DH) or Raine Syndrome causes a lack of mineralisation of the teeth. This results in brittle, brown teeth which are prone to cracking and severe wear. Eventually the inner tooth pulp is exposed causing pain, inflammation, and risk of infection.
An autosomal recessive condition caused by a mutation in the FAM20C gene.
This test is also included in the following Foresight Health® breed packages:
Hytönen MK, Arumilli M, Lappalainen AK, Owczarek-Lipska M, Jagannathan V, Hundi S, Salmela E, Venta P, Sarkiala E, Jokinen T, Gorgas D, Kere J, Nieminen P, Drögemüller C, Lohi H. Molecular Characterization of Three Canine Models of Human Rare Bone Diseases: Caffey, van den Ende-Gupta, and Raine Syndromes. PLoS Genet. 2016 May 17;12(5):e1006037