Foresight Health® Congenital Myasthenic Syndrome
Our Foresight Health® single test for Congenital Myasthenic Syndrome is ideal for breeders and owners who want the reassurance of genetic health testing.
The guideline turnaround time for single tests is approximately 10-12 working days after the swab arrives at the lab.
If you need more than two tests it is often more cost-effective to order the relevant Foresight Health® breed package.
Congenital Myasthenic Syndrome (CMS) is a neuromuscular disease causing weakness in all four limbs which is exacerbated by exercise, it is also visible in reduced reflexes and a shortened gait.
An autosomal recessive condition caused by a mutation in the COLQ gene.
This test is also included in the following Foresight Health® breed packages:
Tsai KL, Vernau KM, Winger K, Zwueste DM, Sturges BK, Knipe M, Williams DC, Anderson KJ, Evans JM, Guo LT, Clark LA, Shelton GD. Congenital myasthenic syndrome in Golden Retrievers is associated with a novel COLQ mutation. J Vet Intern Med. 2020 Jan;34(1):258-265
Rinz CJ, Levine J, Minor KM, Humphries HD, Lara R, Starr-Moss AN, Guo LT, Williams DC, Shelton GD, Clark LA. A COLQ missense mutation in Labrador Retrievers having congenital myasthenic syndrome. PLoS One. 2014 Aug 28;9(8):e106425