Foresight Health® Collie Eye Anomaly

Our Foresight Health® single test for Collie Eye Anomaly is ideal for breeders and owners who want the reassurance of genetic health testing.

The guideline turnaround time for single tests is approximately 10-12 working days after the swab arrives at the lab.

If you need more than two tests it is often more cost-effective to order the relevant Foresight Health^® breed package.

Description

Collie Eye Anomaly (CEA) or Choroidal Hypoplasia is an eye disorder caused when the choroid, a layer in the eye, does not develop properly. Symptoms can vary from mild to severe, from almost normal eyes to retinal detachment and ultimately blindness.

Collie Eye Anomaly is an autosomal recessive condition caused by a mutation in the NHEJ1 gene.

Breeds

This test is also included in the following Foresight Health^® breed packages:

• Australian Shepherd
• Bearded Collie
• Border Collie
• Lancashire Heeler
• Nova Scotia Duck Tolling Retriever
• Rough Collie
• Shetland Sheepdog
• Smooth Collie

Scientific references:

Lowe JK, Kukekova AV, Kirkness EF, Langlois MC, Aguirre GD, Acland GM, Ostrander EA. Linkage mapping of the primary disease locus for collie eye anomaly. Genomics. 2003 Jul;82(1):86-95

Parker HG, Kukekova AV, Akey DT, Goldstein O, Kirkness EF, Baysac KC, Mosher DS, Aguirre GD, Acland GM, Ostrander EA. Breed relationships facilitate fine-mapping studies: a 7.8-kb deletion cosegregates with Collie eye anomaly across multiple dog breeds. Genome Res. 2007 Nov;17(11):1562-71