Foresight Health® Centronuclear Myopathy
Our Foresight Health® single test for Centronuclear Myopathy is ideal for breeders and owners who want the reassurance of genetic health testing.
The guideline turnaround time for single tests is approximately 10-12 working days after the swab arrives at the lab.
If you need more than two tests it is often more cost-effective to order the relevant Foresight Health® breed package.
Centronuclear Myopathy (CNM) is a reduction in muscle fibres causing muscle weakness, abnormal posture and gait, and exercise intolerance and collapse. Symptoms are variable but dogs are generally weak by five months of age and progression of the disorder ends around one year.
Centronuclear Myopathy is an autosomal recessive condition caused by a mutation in the HACD1 gene.
This test is also included in the following Foresight Health® breed packages:
Maurer M, Mary J, Guillaud L, Fender M, Pelé M, Bilzer T, Olby N, Penderis J, Shelton GD, Panthier JJ, Thibaud JL, Barthélémy I, Aubin-Houzelstein G, Blot S, Hitte C, Tiret L. Centronuclear myopathy in Labrador retrievers: a recent founder mutation in the PTPLA gene has rapidly disseminated worldwide. PLoS One. 2012;7(10):e46408
Tiret L, Blot S, Kessler JL, Gaillot H, Breen M, Panthier JJ. The cnm locus, a canine homologue of human autosomal forms of centronuclear myopathy, maps to chromosome 2. Hum Genet. 2003 Sep;113(4):297-306