Foresight Health® Alexander Disease
Our Foresight Health® single test for Alexander Disease is ideal for breeders and owners who want the reassurance of genetic health testing.
Our DNA test results are accepted by the Kennel Club.
Alexander Disease (ALEX), or Swimming Puppy Syndrome, is a neurodegenerative disorder causing limb weakness and muscular contractions in the fore limbs (swimming).
Alexander Disease is an autosomal dominant condition caused by a mutation in the GFAP gene.
This test is also included in the following Foresight Health® breed packages:
The guideline turnaround time for single tests is approximately 10-12 working days after the swab arrives at the lab.
If you need more than two tests it is often more cost-effective to order the relevant Foresight Health® breed package.
Van Poucke, M., Martlé, V., Van Brantegem, L., Ducatelle, R., Van Ham, L., Bhatti, S., & Peelman, L. J. (2016). A canine orthologue of the human GFAP c.716G>A (p.Arg239His) variant causes Alexander disease in a Labrador retriever. European journal of human genetics : EJHG, 24(6), 852–856.