Foresight Health® Osteogenesis Imperfecta


Our Foresight Health® single test for Osteogenesis Imperfecta is ideal for breeders and owners who want the reassurance of genetic health testing.

Our DNA test results are accepted by the Kennel Club.

The guideline turnaround time for single tests is approximately 10-12 working days after the swab arrives at the lab. 

If you need more than two tests it is often more cost-effective to order the relevant Foresight Health® breed package.


Osteogenesis Imperfecta (OI) is a collagen disorder starting at a few weeks of age. It causes lameness and fractures due to thinner than normal bones, as well as loose joints and brittle teeth. Affected dogs are usually euthanised at a young age.

An autosomal recessive condition caused by a mutation in the SERPINH1 or an autosomal dominant condition caused by a mutation in the COL1A1 gene.


This test is also included in the following Foresight Health® breed packages:


Scientific references:

Lindert U, Weis MA, Rai J, Seeliger F, Hausser I, Leeb T, Eyre D, Rohrbach M, Giunta C. Molecular Consequences of the SERPINH1/HSP47 Mutation in the Dachshund Natural Model of Osteogenesis Imperfecta. J Biol Chem. 2015 Jul 17;290(29):17679-17689

Campbell BG, Wootton JA, MacLeod JN, Minor RR. Sequence of normal canine COL1A1 cDNA and identification of a heterozygous alpha1(I) collagen Gly208Ala mutation in a severe case of canine osteogenesis imperfecta. Arch Biochem Biophys. 2000 Dec 1;384(1):37-46

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