Foresight Health® Congenital Stationary Night Blindness

£42.00

Our Foresight Health® single test for Congenital Stationary Night Blindness is ideal for breeders and owners who want the reassurance of genetic health testing.

Our DNA test results are accepted by the Kennel Club.

Description

Congenital Stationary Night Blindness (CSNB), also known as Leber Congenital Amaurosis, is a degenerative disease of the retina beginning with a loss of night vision, progressing to low light and possibly day vision being affected.

An autosomal recessive condition caused by a mutation in the RPE65 gene.

Breeds

This test is also included in the following Foresight Health® breed packages:

 

The guideline turnaround time for single tests is approximately 10-12 working days after the swab arrives at the lab. 

If you need more than two tests it is often more cost-effective to order the relevant Foresight Health® breed package.

 

Scientific references:

Mowat FM, Gervais KJ, Occelli LM, Annear MJ, Querubin J, Bainbridge JW, Smith AJ, Ali RR, Petersen-Jones SM. Early-Onset Progressive Degeneration of the Area Centralis in RPE65-Deficient Dogs. Invest Ophthalmol Vis Sci. 2017 Jun 1;58(7):3268-3277

Kondo M, Das G, Imai R, Santana E, Nakashita T, Imawaka M, Ueda K, Ohtsuka H, Sakai K, Aihara T, Kato K, Sugimoto M, Ueno S, Nishizawa Y, Aguirre GD, Miyadera K. A Naturally Occurring Canine Model of Autosomal Recessive Congenital Stationary Night Blindness. PLoS One. 2015 Sep 14;10(9):e0137072

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