Foresight Health® Cone Degeneration
Our Foresight Health® single test for Cone Degeneration is ideal for breeders and owners who want the reassurance of genetic health testing.
Our DNA test results are accepted by the Kennel Club.
The guideline turnaround time for single tests is approximately 10-12 working days after the swab arrives at the lab.
If you need more than two tests it is often more cost-effective to order the relevant Foresight Health® breed package.
Cone Degeneration (CD) or Achromatopsia causes day blindness or light sensitivity around 8-12 weeks of age, however sight will continue to be normal in low light levels.
An autosomal recessive condition caused by a mutation in the CNGB3 (Alaskan Type) or CNGA3 (Labrador Type) genes.
This test is part of the following Foresight Health® breed packages:
- Alaskan Malamute (Alaskan Type)
- Australian Shepherd (Alaskan Type)
- Cockerdor (Labrador Type)
- Labrador Supplemental (Labrador Type)
Yeh CY, Goldstein O, Kukekova AV, Holley D, Knollinger AM, Huson HJ, Pearce-Kelling SE, Acland GM, Komáromy AM. Genomic deletion of CNGB3 is identical by descent in multiple canine breeds and causes achromatopsia. BMC Genet. 2013 Apr 20;14:27
Sidjanin DJ, Lowe JK, McElwee JL, Milne BS, Phippen TM, Sargan DR, Aguirre GD, Acland GM, Ostrander EA. Canine CNGB3 mutations establish cone degeneration as orthologous to the human achromatopsia locus ACHM3. Hum Mol Genet. 2002 Aug 1;11(16):1823-33