D-Locus (dilute)


The D-Locus is a region of your cat's DNA which controls whether your cat has a diluted coat colour. This is not a colour in itself, but will lighten the coat colour caused by the other colour genes.

Black colours are diluted to grey or blue, chocolate is diluted to lilac, cinnamon to fawn, and red colours are diluted to cream.

The dilute colourations are caused by mutations on the MLPH gene. Dilution is recessive meaning two copies of d are required to dilute coat colours.


Your results will be reported as one combination of the D-locus alleles with the following interpretations.

D/D - non-dilute
D/d - non-dilute carrying dilute
d/d - dilute


Scientific references:

Ishida Y, David VA, Eizirik E, Schäffer AA, Neelam BA, Roelke ME, Hannah SS, O'Brien SJ, Menotti-Raymond M. A homozygous single-base deletion in MLPH causes the dilute coat color phenotype in the domestic cat. Genomics. 2006 Dec;88(6):698-705

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